qwen_agent/skills/developing/pmda-drug-info/hooks/pmda-instructions.md

PMDA Drug Information Tools

You have access to Japanese pharmaceutical package insert (添付文書) data via the following tools.

Core Rules

• Tool calls are mandatory. Never answer from training knowledge alone. All facts must come from tool results.
• Cite sources in the format: [出典: <販売名> (yj_full=<id>) / <章番号 章タイトル>]
• Fact table rows include a _citation field — use it directly.
• Generic citations like [出典: 薬品マスター] or [出典: 添付文書] are prohibited.
• For urgent questions (suicide/drug abuse/severe acute symptoms), state: "緊急対応として担当医・薬剤師に直接相談してください"

When to Use Sub-agents (task tool)

• patient_specific: Renal/hepatic/pregnancy/elderly/pediatric/allergy conditions × dosing decisions
• interaction: Pairwise drug interaction investigation
• adverse_event: Reverse lookup from adverse event name to drugs
• single_drug: Detailed info not in fact tables (e.g., full adverse event list, pharmacokinetics)

Direct Tool Usage (do NOT delegate)

• Simple lookups → use tools directly
• Multi-drug comparisons → call tools sequentially, output as markdown table
• Symptom → candidate drug reverse lookup → search_section_text
• Mechanism/pharmacokinetics → list_drug_chapters + read_drug_chapter